Semaglutide is an FDA-approved medication originally developed to manage Type 2 diabetes. It belongs to a class of drugs called GLP-1 receptor agonists. Because of its significant impact on appetite and weight management, it is now widely used as a highly effective weight loss treatment for adults who are overweight or obese.

Semaglutide mimics a natural hormone in your body called GLP-1 (glucagon-like peptide-1). This hormone targets the areas of the brain that regulate appetite and food intake. By mimicking this hormone, Semaglutide:

• Increases feelings of fullness, so you eat less.
• Slows down gastric emptying, helping you feel satisfied for longer after a meal.
• Reduces food cravings, making it easier to stick to a healthy diet.

At IUVENTUS MEDICAL CENTER, we typically recommend Semaglutide for:

• Adults with a Body Mass Index (BMI) of 30 or higher.
• Adults with a BMI of 27 or higher who also have at least one weight-related medical condition, such as high blood pressure, high cholesterol, or Type 2 diabetes.

Clinical studies have shown that, when combined with diet and exercise, patients taking Semaglutide can lose an average of 15% to 20% of their body weight over 68 weeks. Individual results vary based on your starting weight and lifestyle habits.

Yes. While it was initially for diabetes, the FDA has approved specific brands of Semaglutide (like Wegovy) specifically for chronic weight management in adults without diabetes.

Semaglutide is a once-weekly subcutaneous injection (a small shot under the skin). It can be self-administered in the abdomen, thigh, or upper arm. Our team will provide full training to ensure you are comfortable with the process. Additionally, for your convenience, you may also choose to visit our clinic weekly to have our medical staff administer the injection for you.

Most patients experience mild to moderate side effects as their body adjusts to the medication, including:

• Nausea or vomiting  

• Diarrhea or constipation  

• Stomach pain or bloating  

• Fatigue or headache  

Pro Tip: To minimize nausea, we recommend starting at a low dose and gradually increasing it, staying well-hydrated, and eating smaller, bland meals.

While there are no “forbidden” foods, Semaglutide works best when paired with a nutrient-dense, balanced diet and regular physical activity. We recommend avoiding high-fat or greasy foods initially, as they can worsen nausea.

You should not use Semaglutide if you or anyone in your family has ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) or if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). It is also not recommended for those with a history of pancreatitis.

While everyone’s body responds differently, many patients notice a decrease in appetite and fewer food cravings within the first week or two. Measurable weight loss on the scale typically begins around weeks 3 to 4 as your body adjusts to the medication. Significant progress is usually seen between weeks 8 and 12, especially as you reach your optimal maintenance dose.

There are no official prohibitions against alcohol consumption while on Semaglutide, but moderation is key. We recommend limiting intake because:

• Side Effects: Alcohol can worsen nausea, bloating, and digestive discomfort.

• Blood Sugar: It may increase the risk of low blood sugar (hypoglycemia).

• Empty Calories: Alcohol provides zero nutrition and can slow your weight loss progress.

If you miss a dose of Semaglutide, the protocol depends on how much time has passed:

• Within 5 Days: Take the missed dose as soon as you remember, then return to your normal schedule.

• More than 5 Days: Skip the missed dose and wait for your next regularly scheduled injection day.

• Two or More Weeks: If you miss two consecutive doses, contact our medical team before restarting, as we may need to adjust your dosage to avoid gastrointestinal upset.

To help us create the safest and most effective weight loss plan for you, please review this preparation checklist before your scheduled appointment:

• Gather Your Medical History: Be ready to discuss any past medical conditions, surgeries, and allergies.

• List Your Current Medications: Bring a complete list of all prescriptions, over-the-counter drugs, and supplements you are currently taking.

• Note Your Weight Loss Journey: Think about previous weight loss attempts and your specific long-term goals.

• Hydrate Early: Increase your water intake significantly in the 48 hours leading up to your appointment to help manage potential digestive side effects.

• Eat Mindfully: Transitioning to smaller, high-fiber, and lean-protein meals a few days before starting can help your body adjust more smoothly.

• Prepare Your Questions: Write down any concerns about side effects, the weekly injection process, or how the medication will fit into your lifestyle.